Antiproliferative Activity of <i>Buddleja saligna</i> (Willd.) against Melanoma and <i>In Vivo</i> Modulation of Angiogenesis

• Main Authors: Danielle Twilley (Author), Velaphi C. Thipe (Author), Navneet Kishore (Author), Pierce Bloebaum (Author), Catarina Roma-Rodrigues (Author), Pedro V. Baptista (Author), Alexandra R. Fernandes (Author), Mamoalosi A. Selepe (Author), Lenka Langhansova (Author), Kattesh Katti (Author), Namrita Lall (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Melanoma cells secrete pro-angiogenic factors, which stimulates growth, proliferation and metastasis, and therefore are key therapeutic targets. <i>Buddleja saligna</i> (BS), and an isolated triterpenoid mixture (DT-BS-01) showed a fifty percent inhibitory concentration (IC<sub>50&...