PHACTR1 splicing isoforms and eQTLs in atherosclerosis-relevant human cells

• Hoofdauteurs: Valérie-Anne (Auteur), Mélissa Beaudoin (Auteur), Simon Lalonde (Auteur), Ken Sin Lo (Auteur), Guillaume Lettre (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2018-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Genome-wide association studies (GWAS) have identified a variant (rs9349379) at the phosphatase and actin regulator 1 (PHACTR1) locus that is associated with coronary artery disease (CAD). The same variant is also an expression quantitative trait locus (eQTL) for PHACTR1 in human...