Determination of Ruboxistaurin analysis in rat plasma utilizing LC-MS/MS technique

• Main Authors: Bushra T. AlQuadeib (Author), Fadilah S. Aleanizy (Author), Fulwah Y. Alqahtani (Author), Rehab A. Alshammari (Author), Amal Aldarwesh (Author), Ibrahim Alsarra (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Ruboxistaurin (RBX) used to treat retinopathy in diabetic patients which caused by microvascular damage and leakage which contributes to visual loss. There are no published studies on the use of liquid chromatography-tandem mass spectrometry for development and validation of a simple, se...