Efficient Sustained-Release Nanoparticle Delivery System Protects Nigral Neurons in a Toxin Model of Parkinson's Disease

• Hlavní autoři: Qun Wang (Autor), Rui Ma (Autor), Piaoxue Liu (Autor), Guowang Cheng (Autor), Qi Yang (Autor), Xiaojia Chen (Autor), Zhenfeng Wu (Autor), Dongsheng Yuan (Autor), Tongkai Chen (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2022-08-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Parkinson's disease (PD) is a serious neurodegenerative disease wherein the progressive destruction of dopaminergic neurons results in a series of related movement disorders. Effective oral delivery of anti-Parkinson's drugs is challenging owing to the blood-brain barrier (BBB) and the lim...