Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships

• Główni autorzy: Marialuigia Fantacuzzi (Autor), Ilaria D'Agostino (Autor), Simone Carradori (Autor), Francesco Liguori (Autor), Fabrizio Carta (Autor), Mariangela Agamennone (Autor), Andrea Angeli (Autor), Filomena Sannio (Autor), Jean-Denis Docquier (Autor), Clemente Capasso (Autor), Claudiu T. Supuran (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Vibrio cholerae causes life-threatening infections in low-income countries due to the rise of antibacterial resistance. Innovative pharmacological targets have been investigated and carbonic anhydrases (CAs, EC: 4.2.1.1) encoded by V. cholerae (VchCAs) emerged as a valuable option. Recently, we deve...