Tyrosine 7.43 is important for mu-opioid receptor downstream signaling pathways activated by fentanyl
G protein-coupled receptors can signal through both G proteins and ß-arrestin2. For the µ-opioid receptor (MOR), early experimental evidence from a single study suggested that G protein signaling mediates analgesia and sedation, whereas ß-arrestin signaling mediates respiratory depression and consti...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2022-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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