Nuclear factor erythroid 2-related factor 2 modulates HER4 receptor in ovarian cancer cells to influence their sensitivity to tyrosine kinase inhibitors

• Main Authors: Ibrahim H. Kankia (Author), Poornima Paramasivan (Author), Matthew Elcombe (Author), Simon P. Langdon (Author), Yusuf Y. Deeni (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Nuclear factor erythroid 2-related factor 2 (NRF2) is a key component in the cell's response to oxidative and electrophilic stress and is a transcription factor regulating the expression of a collection of anti-oxidative and cytoprotective genes. Human epidermal growth factor receptor 4 (H...