Prediction of the Drug-Drug Interaction Types with the Unified Embedding Features from Drug Similarity Networks

• Main Authors: Xiao-Ying Yan (Author), Peng-Wei Yin (Author), Xiao-Meng Wu (Author), Jia-Xin Han (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Drug combination therapies are a promising strategy to overcome drug resistance and improve the efficacy of monotherapy in cancer, and it has been shown to lead to a decrease in dose-related toxicities. Except the synergistic reaction between drugs, some antagonistic drug-drug interactions (DDIs) ex...