Extracellular vesicles from human urine-derived stem cells delay aging through the transfer of PLAU and TIMP1

• Main Authors: Shanshan Rao (Author), Zehui He (Author), Zun Wang (Author), Hao Yin (Author), Xiongke Hu (Author), Yijuan Tan (Author), Tengfei Wan (Author), Hao Zhu (Author), Yi Luo (Author), Xin Wang (Author), Hongming Li (Author), Zhenxing Wang (Author), Xinyue Hu (Author), Chungu Hong (Author), Yiyi Wang (Author), Mingjie Luo (Author), Wei Du (Author), Yuxuan Qian (Author), Siyuan Tang (Author), Hui Xie (Author), Chunyuan Chen (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aging increases the risks of various diseases and the vulnerability to death. Cellular senescence is a hallmark of aging that contributes greatly to aging and aging-related diseases. This study demonstrates that extracellular vesicles from human urine-derived stem cells (USC-EVs) efficiently inhibit...