Partial genetic suppression of a loss-of-function mutant of the neuronal ceroid lipofuscinosis-associated protease TPP1 in Dictyostelium discoideum

Neuronal ceroid lipofuscinosis (NCL) is the most common childhood-onset neurodegenerative disease. NCL is inevitably fatal, and there is currently no treatment available. Children with NCL show a progressive decline in movement, vision and mental abilities, and an accumulation of autofluorescent dep...

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Main Authors: Jonathan E. Phillips (Author), Richard H. Gomer (Author)
Format: Book
Published: The Company of Biologists, 2015-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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