Engineering Alginate-Based Dry Powder Microparticles to a Size Suitable for the Direct Pulmonary Delivery of Antibiotics

• Váldodahkkit: Beatriz Arauzo (Dahkki), Álvaro González-Garcinuño (Dahkki), Antonio Tabernero (Dahkki), Javier Calzada-Funes (Dahkki), María Pilar Lobera (Dahkki), Eva M. Martín del Valle (Dahkki), Jesus Santamaria (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2022-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The inhaled route is regarded as one of the most promising strategies as a treatment against pulmonary infections. However, the delivery of drugs in a dry powder form remains challenging. In this work, we have used alginate to form microparticles containing an antibiotic model (colistin sulfate). Th...