Identification of positively selected genes in human pathogenic treponemes: Syphilis-, yaws-, and bejel-causing strains differ in sets of genes showing adaptive evolution.

• Main Authors: Denisa Maděránková (Author), Lenka Mikalová (Author), Michal Strouhal (Author), Šimon Vadják (Author), Ivana Kuklová (Author), Petra Pospíšilová (Author), Lenka Krbková (Author), Pavlína Koščová (Author), Ivo Provazník (Author), David Šmajs (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Pathogenic treponemes related to Treponema pallidum are both human (causing syphilis, yaws, bejel) and animal pathogens (infections of primates, venereal spirochetosis in rabbits). A set of 11 treponemal genome sequences including those of five Treponema pallidum ssp....