hucMSCs Attenuate IBD through Releasing miR148b-5p to Inhibit the Expression of 15-lox-1 in Macrophages

• Main Authors: Jingjing Kang (Author), Zhaoyang Zhang (Author), Jingyan Wang (Author), Gaoying Wang (Author), Yongmin Yan (Author), Hui Qian (Author), Xu Zhang (Author), Wenrong Xu (Author), Fei Mao (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cells (MSCs) exert powerful immunosuppression in inflammatory bowel disease (IBD). Macrophages are the dominant inflammatory cells in enteritis regulated via MSCs. However, the roles of macrophages in the process of MSCs attenuating IBD and the mechanisms of MSCs regulating macropha...