Role and mechanism of CD90+ fibroblasts in inflammatory diseases and malignant tumors

• Główni autorzy: Feng Zeng (Autor), Mengxiang Gao (Autor), Shan Liao (Autor), Zihua Zhou (Autor), Gengqiu Luo (Autor), Yanhong Zhou (Autor)
• Format: Książka
• Wydane: BMC, 2023-02-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Fibroblasts are highly heterogeneous mesenchymal stromal cells, and different fibroblast subpopulations play different roles. A subpopulation of fibroblasts expressing CD90, a 25-37 kDa glycosylphosphatidylinositol anchored protein, plays a dominant role in the fibrotic and pro-inflammatory...