Role and mechanism of CD90+ fibroblasts in inflammatory diseases and malignant tumors

• Autori principali: Feng Zeng (Autore), Mengxiang Gao (Autore), Shan Liao (Autore), Zihua Zhou (Autore), Gengqiu Luo (Autore), Yanhong Zhou (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2023-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Fibroblasts are highly heterogeneous mesenchymal stromal cells, and different fibroblast subpopulations play different roles. A subpopulation of fibroblasts expressing CD90, a 25-37 kDa glycosylphosphatidylinositol anchored protein, plays a dominant role in the fibrotic and pro-inflammatory...