Effects of α-tocopherol on hemolysis and oxidative stress markers on red blood cells in β-thalassemia major

• Main Authors: Nora Sovira (Author), Munar Lubis (Author), Pustika Amalia Wahidiyat (Author), Franciscus D. Suyatna (Author), Djajadiman Gatot (Author), Saptawati Bardosono (Author), Mohammad Sadikin (Author)
• Format: Book
• Published: The Korean Pediatric Society, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background The accumulation of unpaired α-globin chains in patients with β-thalassemia major may clinically create ineffective erythropoiesis, hemolysis, and chronic anemia. Multiple blood transfusions and iron overload cause cellular oxidative damage. However, α-tocopherol, an antioxidant, is a pot...