Effects of α-tocopherol on hemolysis and oxidative stress markers on red blood cells in β-thalassemia major

• 主要な著者: Nora Sovira (著者), Munar Lubis (著者), Pustika Amalia Wahidiyat (著者), Franciscus D. Suyatna (著者), Djajadiman Gatot (著者), Saptawati Bardosono (著者), Mohammad Sadikin (著者)
• フォーマット: 図書
• 出版事項: The Korean Pediatric Society, 2020-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background The accumulation of unpaired α-globin chains in patients with β-thalassemia major may clinically create ineffective erythropoiesis, hemolysis, and chronic anemia. Multiple blood transfusions and iron overload cause cellular oxidative damage. However, α-tocopherol, an antioxidant, is a pot...