Proteomics Analysis of Monocyte-Derived Hepatocyte-Like Cells Identifies Integrin Beta 3 as a Specific Biomarker for Drug-Induced Liver Injury by Diclofenac

• Asıl Yazarlar: Diana Dragoi (Yazar), Andreas Benesic (Yazar), Garwin Pichler (Yazar), Nils A. Kulak (Yazar), Harald S. Bartsch (Yazar), Alexander L. Gerbes (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Idiosyncratic drug-induced liver injury (iDILI) is a major cause of acute liver failure resulting in liver transplantation or death. Prediction and diagnosis of iDILI remain a great challenge, as current models provide unsatisfying results in terms of sensitivity, specificity, and prognostic value....