THE EXPERIENCE OF SWITCHING TO THE SECOND TNF INHIBITOR IN A PATIENT WITH SEVERE JUVENILE POLYARTHRITIS AND RESISTANCE TO THE FIRST TNF-BLOCKER

• Main Authors: Ekaterina I. Alexeeva (Author), Tatiana M. Dvoryakovskaya (Author), Rina V. Denisova (Author), Olga L. Lomakina (Author), Anna V. Karaseva (Author)
• Format: Book
• Published: "Paediatrician" Publishers LLC, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The article presents  a case  of a severe  progressive  course  of polyarticular  juvenile idiopathic arthritis,  debuting  at an early age, refractory to the therapy with methotrexate, cyclosporine, and glucocorticosteroids.  A clinical example demonstrates that switching to the second TNF  inhibit...