Overexpression of the vitamin D receptor (VDR) induces skeletal muscle hypertrophy

• Main Authors: Joseph J. Bass (Author), Asif Nakhuda (Author), Colleen S. Deane (Author), Matthew S. Brook (Author), Daniel J. Wilkinson (Author), Bethan E. Phillips (Author), Andrew Philp (Author), Janelle Tarum (Author), Fawzi Kadi (Author), Ditte Andersen (Author), Amadeo Muñoz Garcia (Author), Ken Smith (Author), Iain J. Gallagher (Author), Nathaniel J. Szewczyk (Author), Mark E. Cleasby (Author), Philip J. Atherton (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The Vitamin D receptor (VDR) has been positively associated with skeletal muscle mass, function and regeneration. Mechanistic studies have focused on the loss of the receptor, with in vivo whole-body knockout models demonstrating reduced myofibre size and function and impaired muscle deve...