Amelioration of lipophilic compounds in regards to bioavailability as self-emulsifying drug delivery system (SEDDS)

• Hauptverfasser: Pragya Baghel (VerfasserIn), Amit Roy (VerfasserIn), Shekhar Verma (VerfasserIn), Trilochan Satapathy (VerfasserIn), Sanjib Bahadur (VerfasserIn)
• Format: Buch
• Veröffentlicht: SpringerOpen, 2020-06-01T00:00:00Z.
• Schlagworte: article
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Abstract Background High lipophilicity and poor aqueous solubility are the endemic problems of new drug molecules. Sixty to seventy percent of these drugs are unable to solubilize completely in aqueous media, or have very low permeability. This hampers their oral absorption and further leads to thei...