Investigating the role of a Tannerella forsythia HtrA protease in host protein degradation and inflammatory response

• Main Authors: Susanne Bloch (Author), Fiona F. Hager-Mair (Author), Johanna Bacher (Author), Markus B. Tomek (Author), Bettina Janesch (Author), Oleh Andrukhov (Author), Christina Schäffer (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionDegradation of host proteins by bacterial proteases leads to the subversion of the host response and disruption of oral epithelial integrity, which is considered an essential factor in the progression of periodontitis. High-temperature requirement A (HtrA) protease, which is critical for...