miR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons

• मुख्य लेखकों: Anna-Elisa Roser (लेखक), Lucas Caldi Gomes (लेखक), Rashi Halder (लेखक), Gaurav Jain (लेखक), Fabian Maass (लेखक), Lars Tönges (लेखक), Lars Tatenhorst (लेखक), Mathias Bähr (लेखक), André Fischer (लेखक), Paul Lingor (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2018-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Parkinson's disease (PD) is the second-most-frequent neurodegenerative disorder worldwide. One major hallmark of PD is the degeneration of dopaminergic (DA) neurons in the substantia nigra. Glial cell line-derived neurotrophic factor (GDNF) potently increases DA neuron survival in models of PD;...