Activation of Nicotinic Acetylcholine α7 Receptor Attenuates Progression of Monocrotaline-Induced Pulmonary Hypertension in Rats by Downregulating the NLRP3 Inflammasome

• 主要な著者: Yan Deng (著者), Sheng-Lan Guo (著者), Bin Wei (著者), Xing-Cui Gao (著者), Ying-Chuan Zhou (著者), Jia-Quan Li (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background: Inflammation and altered immunity contribute to the development of pulmonary arterial hypertension (PH). The alpha 7 nicotinic acetylcholine receptor (α7nAChR) possesses anti-inflammatory activities. The current study was performed to investigate the effects of a selective α7nAChR agonis...