Differential Effects of Purinergic Signaling in Gastric Cancer-Derived Cells Through P2Y and P2X Receptors

• Main Authors: María José Hevia (Author), Patricio Castro (Author), Katherine Pinto (Author), Mauricio Reyna-Jeldes (Author), Felipe Rodríguez-Tirado (Author), Claudia Robles-Planells (Author), Sebastián Ramírez-Rivera (Author), Juan Andrés Madariaga (Author), Felipe Gutierrez (Author), Javier López (Author), Marcelo Barra (Author), Erwin De la Fuente-Ortega (Author), Giuliano Bernal (Author), Claudio Coddou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastric cancer (GC) is the one of the most prevalent cancers and one of the leading causes of cancer-induced deaths. Previously, we found that the expression of purinergic P2Y2 receptor (P2Y2R) is increased in GC samples as compared to adjacent healthy mucosa taken from GC-diagnosed patients. In thi...