Cilomilast Modulates Rhinovirus-Induced Airway Epithelial ICAM-1 Expression and IL-6, CXCL8 and CCL5 Production

• 主要な著者: Jie Zhu (著者), Michael R. Edwards (著者), Simon D. Message (著者), Luminita A. Stanciu (著者), Sebastian L. Johnston (著者), Peter K. Jeffery (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

<b>Background:</b> Cilomilast, a phosphodiesterase-4 (PDE4) selective inhibitor, has anti-inflammatory effects in vitro and in vivo and reduces COPD exacerbations. We tested the hypothesis that cilomilast inhibits virus-induced airway epithelial intercellular adhesion molecule-1 (ICAM-1)...