Population pharmacokinetic modeling and simulations of berotralstat for prophylactic treatment of attacks of hereditary angioedema

Abstract Hereditary angioedema (HAE) is an autosomal dominant disorder characterized by recurrent episodes of swelling of the skin, larynx, gastrointestinal tract, genitals, and extremities that can be disruptive to patient quality of life. Dysregulation of plasma kallikrein activity leads to increa...

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Main Authors: Amanda Mathis (Author), Mark Sale (Author), Melanie Cornpropst (Author), William P. Sheridan (Author), Shu Chin Ma (Author)
Format: Book
Published: Wiley, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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