Ganglioside GD3 synthase (GD3S), a novel cancer drug target

• Main Authors: Jinyi Liu (Author), Xiangjin Zheng (Author), Xiaocong Pang (Author), Li Li (Author), Jinhua Wang (Author), Cui Yang (Author), Guanhua Du (Author)
• Format: Book
• Published: Elsevier, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gangliosides are a class of important glycosphingolipids containing sialic acid that are widely distributed on the outer surface of cells and are abundantly distributed in brain tissue. Disialoganglioside with three glycosyl groups (GD3) and disialoganglioside with two glycosyl groups (GD2) are mark...