Fibrin‐specific poly(N‐isopropylacrylamide) nanogels for targeted delivery of tissue‐type plasminogen activator to treat thrombotic complications are well tolerated in vivo

• Main Authors: Emily P. Mihalko (Author), Kimberly Nellenbach (Author), Manasi Krishnakumar (Author), Nina Moiseiwitsch (Author), Jennifer Sollinger (Author), Brian C. Cooley (Author), Ashley C. Brown (Author)
• Format: Book
• Published: Wiley, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Targeted drug delivery for maintaining blood fluidity can reduce the risks associated with systemic anticoagulants that can lead to off‐target bleeding. Recently, there has been much interest in targeted delivery of tissue‐type plasminogen activator (tPA) for treating thrombotic complicatio...