The repair gene <em>BACH1</em> - a potential oncogene

• Main Authors: Katheeja Muhseena N (Author), Sooraj Mathukkada (Author), Shankar Prasad Das (Author), Suparna Laha (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACH1 encodes for a protein that belongs to RecQ DEAH helicase family and interacts with the BRCT repeats of BRCA1. The N-terminus of BACH1 functions in DNA metabolism as DNA-dependent ATPase and helicase. The C-terminus consists of BRCT domain, which interacts with BRCA1 and this interaction is one...