Disaccharide trehalose in experimental therapies for neurodegenerative disorders: Molecular targets and translational potential

• Main Authors: Alexander B. Pupyshev (Author), Tatyana P. Klyushnik (Author), Anna A. Akopyan (Author), Sandeep Kumar Singh (Author), Maria A. Tikhonova (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Induction of autophagy is a prospective approach to the treatment of neurodegeneration. In the recent decade, trehalose attracted special attention. It is an autophagy inducer with negligible adverse effects and is approved for use in humans according to FDA requirements. Trehalose has a therapeutic...