Antisense oligonucleotide and adjuvant exercise therapy reverse fatigue in old mice with myotonic dystrophy
Patients with myotonic dystrophy type 1 (DM1) identify chronic fatigue as the most debilitating symptom, which manifests in part as prolonged recovery after exercise. Clinical features of DM1 result from pathogenic gain-of-function activity of transcripts containing an expanded microsatellite CUG re...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2021-03-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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