Identification of mosquito proteins that differentially interact with alphavirus nonstructural protein 3, a determinant of vector specificity.

• Main Authors: Nathaniel M Byers (Author), Paul L Burns (Author), Olga Stuchlik (Author), Matthew S Reed (Author), Jeremy P Ledermann (Author), Jan Pohl (Author), Ann M Powers (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chikungunya virus (CHIKV) and the closely related onyong-nyong virus (ONNV) are arthritogenic arboviruses that have caused significant, often debilitating, disease in millions of people. However, despite their kinship, they are vectored by different mosquito subfamilies that diverged 180 million yea...