Immunomodulation with minocycline rescues retinal degeneration in juvenile neuronal ceroid lipofuscinosis mice highly susceptible to light damage

Juvenile neuronal ceroid lipofuscinosis (jNCL) is a rare but fatal inherited lysosomal storage disorder mainly affecting children. The disease is caused by mutations in the CLN3 gene that lead to the accumulation of storage material in many tissues, prominent immune responses and neuronal degenerati...

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Main Authors: Katharina Dannhausen (Author), Christoph Möhle (Author), Thomas Langmann (Author)
Format: Book
Published: The Company of Biologists, 2018-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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