Immunomodulation with minocycline rescues retinal degeneration in juvenile neuronal ceroid lipofuscinosis mice highly susceptible to light damage
Juvenile neuronal ceroid lipofuscinosis (jNCL) is a rare but fatal inherited lysosomal storage disorder mainly affecting children. The disease is caused by mutations in the CLN3 gene that lead to the accumulation of storage material in many tissues, prominent immune responses and neuronal degenerati...
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Main Authors: | Katharina Dannhausen (Author), Christoph Möhle (Author), Thomas Langmann (Author) |
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Format: | Book |
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The Company of Biologists,
2018-09-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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