Activation of NLRP3 Inflammasome in the Skin of Patients with Systemic and Cutaneous Lupus Erythematosus

• Main Authors: Katariina Mähönen (Author), Annika Hau (Author), Vincent Bondet (Author), Darragh Duffy (Author), Kari K. Eklund (Author), Jaana Panelius (Author), Annamari Ranki (Author)
• Format: Book
• Published: Medical Journals Sweden, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

NLRP3 inflammasome is suggested to contribute to the complex pathogenesis of systemic lupus erythematosus, but its role in cutaneous lupus erythematosus has not been addressed. This study investigated the expression of NLRP3 inflammasome components and levels of type I interferons in the skin of 20...