Orosomucoid 2 is an endogenous regulator of neuronal mitochondrial biogenesis and promotes functional recovery post-stroke

• Main Authors: Kai Jing (Author), Ruinan Gu (Author), Feng Chen (Author), Jingjing Wan (Author), Yang Sun (Author), Pengyue Guo (Author), Fei Chen (Author), Jiayi Feng (Author), Jinmin Guo (Author), Xia Liu (Author)
• Format: Book
• Published: Elsevier, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Development of functional recovery therapies is critical to reduce the global impact of stroke as the leading cause of long-term disability. Our previous studies found that acute-phase protein orosomucoid (ORM) could provide an up to 6 h therapeutic time window to reduce infarct volume in acute isch...