Quantitative analysis of intraneuronal transport in human iPS neurons

• Main Authors: Haruko Nakamura (Author), Naoya Yamashita (Author), Yuri Kanamaru (Author), Takahiko Tachibana (Author), Yuko Sekino (Author), Sandy Chen (Author), Toshiyuki Gotoh (Author), Fumiaki Tanaka (Author), Yoshio Goshima (Author)
• 格式: 圖書
• 出版: Elsevier, 2015-08-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Induced pluripotent stem (iPS) cells are promising tools to investigate disease mechanism and develop new drugs. Intraneuronal transport, which is fundamental for neuronal survival and function, is vulnerable to various pharmacological and chemical agents and is disrupted in some neurodegenerative d...