USP9X-enriched MSC-sEV inhibits LSEC angiogenesis in MASH mice by downregulating the IκBα/NF-κB/Ang-2 pathway

• Egile Nagusiak: Yanjin Wang (Egilea), Chen Wang (Egilea), Fuji Yang (Egilea), Yifei Chen (Egilea), Yujie Shi (Egilea), Ruizi Xu (Egilea), Zhuan Zhang (Egilea), Yongmin Yan (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2024-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Pathological angiogenesis of liver sinusoidal endothelial cells (LSEC) plays a crucial role in the progression of metabolic dysfunction-associated steatohepatitis (MASH)-induced liver fibrosis. Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEV) have shown promising therapeutic pote...