High throughput selection of effective serodiagnostics for Trypanosoma cruzi infection.

• Main Authors: Gretchen Cooley (Author), R Drew Etheridge (Author), Courtney Boehlke (Author), Becky Bundy (Author), D Brent Weatherly (Author), Todd Minning (Author), Matthew Haney (Author), Miriam Postan (Author), Susana Laucella (Author), Rick L Tarleton (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2008-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diagnosis of Trypanosoma cruzi infection by direct pathogen detection is complicated by the low parasite burden in subjects persistently infected with this agent of human Chagas disease. Determination of infection status by serological analysis has also been faulty, largely due to the lack of well-c...