β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells

• Main Authors: Sajid Jalal (Author), Ting Zhang (Author), Jia Deng (Author), Jie Wang (Author), Ting Xu (Author), Tianhua Zhang (Author), Chuanxin Zhai (Author), Ruqiang Yuan (Author), Hongming Teng (Author), Lin Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Melanoma is a highly aggressive skin cancer and accounts for most of the skin cancer-related deaths. The efficacy of current therapies for melanoma remains to be improved. The isopropanolamine derivative of β-elemene LXX-8250 was reported to present better water solubility and stronger toxicity to t...