Spontaneous germinal centers and autoimmunity
Germinal centers (GCs) are dynamic microenvironments that form in the secondary lymphoid organs and generate somatically mutated high-affinity antibodies necessary to establish an effective humoral immune response. Tight regulation of GC responses is critical for maintaining self-tolerance. GCs can...
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Taylor & Francis Group,
2017-01-01T00:00:00Z.
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