Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells

• 主要な著者: Anqi Wang (著者), Jiayu Liu (著者), Yuhan Yang (著者), Zhejie Chen (著者), Caifang Gao (著者), Zhanguo Wang (著者), Chaomei Fu (著者), Liang Zou (著者), Shengpeng Wang (著者)
• フォーマット: 図書
• 出版事項: BMC, 2021-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Shikonin (SKO) is a natural naphthoquinone derived from Chinese herbal medicine Arnebiae Radix with high development potentials due to its anti-inflammatory and anti-tumor activities. Overwhelming evidences have indicated that SKO can induce both necrosis and apoptosis in cancer...