Selective inhibitors for JNK signalling: a potential targeted therapy in cancer

• Main Authors: Qinghua Wu (Author), Wenda Wu (Author), Vesna Jacevic (Author), Tanos C. C. Franca (Author), Xu Wang (Author), Kamil Kuca (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

c-Jun N-terminal kinase (JNK) signalling regulates both cancer cell apoptosis and survival. Emerging evidence show that JNK promoted tumour progression is involved in various cancers, that include human pancreatic-, lung-, and breast cancer. The pro-survival JNK oncoprotein functions in a cell conte...