Morin hydrate downregulates inflammation‐mediated nitric oxide overproduction and potentiates antioxidant mechanism against anticancer drug doxorubicin oxidative hepatorenal toxicity in rats

Morin hydrate downregulates inflammation‐mediated nitric oxide overproduction and potentiates antioxidant mechanism against anticancer drug doxorubicin oxidative hepatorenal toxicity in rats

Objective: Doxorubicin (DOX) is a frontline antineoplastic drug that kills cancer cells through genotoxic mechanism; however, it induces organ toxicities. This study assayed whether morin hydrate (MOH) could abrogate DOX hepatorenal toxicity in rats.Materials and Methods: There were 4 groups of rats...

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Main Authors: Ademola Famurewa (Author), Chima Ekeleme-Egedigwe (Author), Patience Ogbu (Author), Ayodeji Ajibare (Author), Moshood Folawiyo (Author), Doris Obasi (Author), Arunaksharan Narayanankutty (Author)
Format: Book
Published: Mashhad University of Medical Sciences, 2023-09-01T00:00:00Z.
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