Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming

In the early twentieth century, Otto Heinrich Warburg described an elevated rate of glycolysis occurring in cancer cells, even in the presence of atmospheric oxygen (the Warburg effect). Despite the inefficiency of ATP generation through glycolysis, the breakdown of glucose into lactate provides can...

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Bibliographic Details
Main Authors: Bernadette M. M. Zwaans (Author), David B. Lombard (Author)
Format: Book
Published: The Company of Biologists, 2014-09-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available