IL-4 receptor dependent expansion of lung CD169+ macrophages in microfilaria-driven inflammation.

• Main Authors: Frédéric Fercoq (Author), Estelle Remion (Author), Stefan J Frohberger (Author), Nathaly Vallarino-Lhermitte (Author), Achim Hoerauf (Author), John Le Quesne (Author), Frédéric Landmann (Author), Marc P Hübner (Author), Leo M Carlin (Author), Coralie Martin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lung disease is regularly reported in human filarial infections but the molecular pathogenesis of pulmonary filariasis is poorly understood. We used Litomosoides sigmodontis, a rodent filaria residing in the pleural cavity responsible for pleural inflammation, to model responses to human filarial in...