In vitro and in vivo characterization of Entacapone-loaded nanostructured lipid carriers developed by quality-by-design approach

• Main Authors: Yogeeta Agrawal (Author), Kiran Patil (Author), Hitendra Mahajan (Author), Mrugendra Potdar (Author), Pratiksha Joshi (Author), Kartik Nakhate (Author), Charu Sharma (Author), Sameer N. Goyal (Author), Shreesh Ojha (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Entacapone, a reversible catechol-o-methyl transferase inhibitor, is used to enhance the action of dopamine agonists by reducing their metabolism and the 'Wearing-off' effects associated with long-term use in the treatment of Parkinson's disease. It is used as an adjunct to levodopa/C...