Choroid plexus CCL2‒CCR2 signaling orchestrates macrophage recruitment and cerebrospinal fluid hypersecretion in hydrocephalus

• Main Authors: Qiguang Wang (Author), Fei Liu (Author), Yue Li (Author), Huan Zhang (Author), Xin Qi (Author), Ke Wu (Author), Yi Zhang (Author), Shenglan You (Author), Wenke Liu (Author), Xuhui Hui (Author), Hanmei Li (Author), Lei Zhu (Author), Huile Gao (Author), Jian Cheng (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The choroid plexus (ChP) serves as the principal origin of cerebrospinal fluid (CSF). CSF hypersecretion due to ChP inflammation has emerged as an important pathogenesis of hydrocephalus recently. Nevertheless, the precise mechanisms of ChP inflammation and the ensuing CSF hypersecretion in hydrocep...