Improved non-invasive positron emission tomographic imaging of chemotherapy-induced tumor cell death using Zirconium-89-labeled APOMAB®

• Principais autores: Vasilios Liapis (Autor), William Tieu (Autor), Stacey E. Rudd (Autor), Paul S. Donnelly (Autor), Nicole L. Wittwer (Autor), Michael P. Brown (Autor), Alexander H. Staudacher (Autor)
• Formato: Livro
• Publicado em: SpringerOpen, 2020-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Purpose The chimeric monoclonal antibody (mAb) chDAB4 (APOMAB®) targets the Lupus associated (La)/Sjögren Syndrome-B (SSB) antigen, which is over-expressed in tumors but only becomes available for antibody binding in dead tumor cells. Hence, chDAB4 may be used as a novel theranostic tool to...