Using superparamagnetic iron oxide nanoparticles to enhance bioavailability of quercetin in the intact rat brain

• Main Authors: Rezvan Enteshari Najafabadi (Author), Nasrin Kazemipour (Author), Abolghasem Esmaeili (Author), Siamak Beheshti (Author), Saeed Nazifi (Author)
• Format: Book
• Published: BMC, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Quercetin (QT) as a bioactive flavonoid has a potential therapeutic activity for numerous neuronal injuries and neurodegenerative diseases. However, the low absorption rate of QT, especially through the blood-brain barrier, restricts its bioactivity in the body. The current resea...