Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease.

• Autori principali: Nisha Jain Garg (Autore), Kizhake V Soman (Autore), Maria P Zago (Autore), Sue-Jie Koo (Autore), Heidi Spratt (Autore), Susan Stafford (Autore), Zinzi N Blell (Autore), Shivali Gupta (Autore), Julio Nuñez Burgos (Autore), Natalia Barrientos (Autore), Allan R Brasier (Autore), John E Wiktorowicz (Autore)
• Natura: Libro
• Pubblicazione: Public Library of Science (PLoS), 2016-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Trypanosoma cruzi (Tc) infection causes chagasic cardiomyopathy; however, why 30-40% of the patients develop clinical disease is not known. To discover the pathomechanisms in disease progression, we obtained the proteome signature of peripheral blood mononuclear cells (PBMCs) of normal healthy contr...